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Why did HCG levels rise after receiving the prescribed medication?

2 weeks ago

after receiving methotrexate on 4th day my hcg levels in the morning went to 4300 and then four hours later to 5900

Asked By Sobha | Female | Age 22

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2 weeks ago

Answers (1)

Pristyn Care Team

Simplifying Healthcare

Jul 07 2026

A rise in Beta hCG during the first few days after methotrexate can occur and does not necessarily mean the treatment has failed. The response to methotrexate is typically assessed using serial Beta hCG measurements, with the key comparison usually being between day 4 and day 7.

Continue follow up with your gynecologist and have your Beta hCG checked as advised. Seek immediate medical care if you develop severe abdominal pain, heavy bleeding, dizziness, or fainting, as these may indicate a complication.

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