Pregnant Female holding Dolo 650 in her hand

Dolo 650 is a widely used medicine that relieves pain and fever. The active ingredient in Dolo 650 is paracetamol and it acts by increasing the pain threshold and blood flow across the body. 

What is Dolo 650 used for?

Dolo 650 can be used to treat the following- 

  • Fever
  • Headache
  • Cold
  • Joint pain
  • Flu
  • Ear pain
  • Toothache
  • Post-immunization pyrexia
  • Cephalalgia
  • Arthritis

 

Is Dolo 650 safe during pregnancy?

Yes, Dolo 650 is safe during pregnancy. But, make sure to not over-use this medicine. In case you have the same problem repeatedly, it is better to consult a doctor before taking the medicine again. Consult an expert now to know more about the safe use of Dolo 650 in pregnancy. 

In some cases, Dolo 650 can have some side effects, including- 

 

  • Feeling of sickness
  • Nausea
  • Shortness of breath
  • Rashes
  • Redness
  • Swelling 
  • Liver damage
  • Allergic reactions
  • Asphyxiation
  • Allergen

How can Dolo 650 be used?

Young pregnant woman having pain

Dolo 650 is usually taken orally but can also be used intravenously. Dolo 650 is not suggested to a female if she is allergic to paracetamol. It can be administered safely along with cetirizine, ibuprofen, amoxicillin, fexofenadine, warfarin, tamsulosin, codeine, erythromycin, metronidazole, rabeprazole tramadol, azithromycin, and naproxen. But, Dolo 650 should not be used to treat any sort of infection. 

What drugs can interact with Dolo 650?

Dolo 650 can interact with the following drugs-

  • Juxtapid mipomersen
  • Prilocaine
  • Ketoconazole
  • Leflunomide
  • Teriflunomide

Under what conditions Dolo 65 should not be taken?

A female should strictly avoid Dolo 650 in the following conditions or cases- 

 

  • Activities requiring high mental alertness
  • Chronic malnutrition
  • Hypersensitivity
  • Hepatic impairment 
  • An upcoming surgical procedure

 

Is Dolo 650 safe during pregnancy and breastfeeding?

sick pregnant female wearing a mask

Yes, Dolo 650 is safe and can be taken sometimes during pregnancy and while breastfeeding. However, do not take medicine regularly. If you feel the need, consult a doctor first. 

Should Dolo 650 be taken before or after eating food?

Dolo 650 should be taken after a meal. Avoid taking this medicine on an empty stomach. If you do not feel like eating or have nausea, have a light meal or just a few bites but do not take it empty stomach. 

 

What are some safe substitutes for Dolo 650?

  • Pharmacol 650 mg 
  • Calpol 650 mg
  • Doliprane 650 mg 
  • PUC 650 mg
  • Pcm 650 mg 

What drugs should be avoided while taking Dolo 650?

Dolo 650 has drug interactions with the following, so avoid taking it along with these  

  • Carbamazepine
  • Isoniazid
  • Phenytoin
  • Sodium Nitrite
  • Leflunomide
  • Prilocaine
  • Naltrexone

Can I overdose with Dolo 650?

On taking repeatedly, the female may have overdosed on this medicine. Symptoms of overdose of dolo 650 can include- 

  • Vomiting
  • Nausea
  • Profuse sweating
  • General tiredness

In severe cases of overdose, the female may have the following- 

  • Kidney damage
  • Liver disease
  • Decreased platelet

Call your doctor right away in case you feel you have had an overdose of this drug.

Overview

Pregnant Female holding Dolo 650 in her hand at doctor's office

Dolo 650 is a good choice to treat fever and pain and with mild dosage, has very few side effects. However, it should not be taken regularly. If you face the same problems repeatedly during pregnancy, avoid taking the pill without consulting your doctor. 

Some safety measures for Dolo 650 during pregnancy-

  • Do not use Dolo 650 without consulting your doctor as it can lead to complications.
  • Do not risk your health with self-medication and take your doctor’s advice.
  • Do not stop the dosage if it is prescribed by your doctor.
  • Unless your doctor prescribes, do not break the drug schedule.
  • Do not take a double dose if you skipped a previous one. Talk to your doctor in case you skipped a dose or vomited (for any reason)  after the medicine.
  • Store the medicine at room temperature (23 – 25.5 °C) away from direct sunlight and moisture. Do not store this medicine in your bathroom cabinets. 
  • Keep the medicine out of the reach of children and pets.

 

Also Read:

Pristyn Care Team
Author Pristyn Care Team

Updated on 26th September 2025

Views: 51,772

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