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About IVF

In-vitro Fertilization or IVF is a common assistive reproductive procedure that helps couples conceive. As the name suggests, IVF is a reproductive treatment where a female egg is fertilized by the male sperm in a tube or a glass dish, at a specialized infertility lab. Once the embryo has been successfully formed, it is implanted in the uterus.

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Overview

IVF
Need for IVF Treatment
  • Avoid standing for long periods of time
  • Wear compression stockings
  • Refrain from smoking
  • Maintain a healthy body weight
  • Maintain a healthy lifestyle
  • Sit while elevating your legs to promote blood circulation
Benefits of IVF Treatment
  • IVF works when other infertility treatments fail
  • You can use donated eggs or sperm
  • You have control over your pregnancy timing
  • Increases the chances of conception
  • Decreases the chances of miscarriage
  • Increases the chances of having a healthy baby
  • Anyone can use IVF
Who Should Consider IVF Treatment?
  • Male with low sperm counts
  • Female suffering endometriosis
  • A female suffering from problems with the uterus
  • A female with ovulation disorders
  • Male with low sperm motility
Different Types Of IVF Treatment
  • IVF + Frozen Embryo Transfer (FET)
  • IVF + Elective Single Embryo Transfer (eSET)
  • IVF + Intracytoplasmic Injection (ICSI)
  • IVF + Egg Donor
  • IVF + Donor Sperm
  • Natural IVF
  • Mini IVF (Minimal Stimulation)
Why Choose Pristyn Care for IVF treatment?
  • Highly experienced fertility specialists
  • Home sample collection facility
  • Confidential consultation
  • No-cost EMI provision
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Treatment

Diagnosis

Before proceeding with IVF, the fertility specialist may need to do multiple tests to determine the problem. If the couple is planning for IVF or if the fertility doctor thinks IVF can help a couple, he or she would want both the male and female to undergo the following tests-

  • For males:- Semen analysis, hormone testing, vasography, MRI, ultrasound, and genetic testing
  • For females:- Ovulation testing, hysteroscopy, and test for ovarian reserve

Procedure

  • Step 1: Beginning of IVF treatment – The IVF treatment journey begins with the doctor determining the best time during your menstrual cycle. IVF treatment requires several eggs to mature.
  • Step 2: Ovarian stimulation- Ovarian stimulation is the first and the most important step of the process where the doctor stimulates the ovaries to promote the growth of the follicles that contain the eggs. The common hormones that are used to stimulate the follicles are Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). Once injected, the IVF doctor, along with the team, monitors how the ovaries respond to the medications.
  • Step 3: Trigger Injections – Once the doctor sees that the egg follicles in the ovaries are enough, the doctor will stop the LH and FSH injections and will recommend the time when you need to administer trigger injections. The trigger injection includes injecting human chorionic gonadotropin (hCG) to mature the eggs and help them get released from the ovarian follicle wall.
  • Step 4: Egg retrieval- Egg retrieval or ‘egg picking stage’ is a daycare procedure done under general anesthesia. During the procedure, the doctor inserts a fine needle with an ultrasound-guided probe through the vaginal canal of the woman to retrieve her mature eggs. The procedure generally does not take more than 30 minutes. On average, 8-15 eggs are collected during this process. Once the eggs are retrieved, the patient is allowed to go home and rest. It is best if the patient is accompanied by her partner or someone else who can help her drive and reach home safely.
  • Step 5: Sperm collection – After retrieving/ collecting the eggs, the IVF doctor will need to collect the sperm from the male partner. At this stage, the male partner will be asked to produce his semen specimen. Every IVF lab will have a dedicated room where the male can masturbate and give his sperm/ semen specimen. The male partner can produce his semen specimen at home or at the clinic where the semen specimen would be stored. In case the couple wants to use donor sperm or frozen sperm, the IVF team will get it ready in the lab. The collected sperm sample is washed with medicine under a microscope to get rid of all sorts of dirt and debris. This cleansing is done to find out the healthiest sperm that can fertilize the eggs. A perfect healthy sperm is one that is not very long and not too short either, not too fat or not too thin.
  • Step 6: Fertilization- Once the sperm is washed and concentrated, it is placed in an incubator along with the eggs for fertilization. The process is very similar to that of natural fertilization, where ‘sperm meets eggs’ inside a human body.
  • Step 7: Embryo development- The eggs that the egg would fertilize would then turn into an embryo. The IVF specialist will collect the embryo, place it in a special incubator and monitor its growth for the next 4-6 days. The developed embryo would be mixed with amino acids to its growth. If the growth of the embryo is consistent, it is likely to turn into a 4-8 cell embryo by the 4th day.
  • Step 8: Embryo transfer- Embryo transfer refers is a process where the developed embryo is transferred from the incubator and implanted in the uterine wall. This process is quick, does not take more than 20 minutes, and can be done at the clinic of the doctor. During the process, the woman would be asked to lie down on her back and spread her legs. The doctor will collect the embryo with a very soft, flexible, and thin catheter. Using a speculum, the doctor will open the cervix and insert the catheter through the cervix into the uterus to plant the embryo.

An abdominal ultrasound is conducted to make sure that the tip of the catheter places the embryo at the best location for embryo implantation. After the embryo transplant is over, the woman is allowed to head home.

  • Step 9: Pregnancy check-The woman would be called to the clinic after 2 weeks for a blood test. If the blood test shows the presence of hCG in it, the pregnancy is successful. If the results are positive, the doctor would suggest the best pregnancy care tips to the woman and encourage her to limit strenuous physical activities. If the blood test does not show the presence of hCG, it indicates that the pregnancy is not successful. In that case, the doctor may either repeat the entire process once again or may determine another line of treatment.

In Our Doctor's Word

Dr. Janani Manoharan

MBBS, MD - Obstetrics & Gynaecology, DMAS

15 Years Experience

" The most common fear among my patients is- 'Are IVF babies healthy?'" Well yes, absolutely! An IVF baby is as healthy as any other naturally conceived child. Millions of babies have birthed since the first IVF and there are no recorded long term difference in their health/ immunity. The method only differs them based on their way of conception and not health. Infact, the quality of your baby's health depends directly on the quality of you and your partner's eggs, your diet, gestation period, and your physical and mental health throughout the pregnancy. As long as these factors are in place and you manage your stress pointers, your baby's health will be absolutely perfect!"

Frequently Asked Questions

What is the cost of IVF treatment in Navi mumbai?

The average cost of IVF in Navi mumbai ranges from Rs. 95,000 to Rs. 1,25,000. But this is not the final or fixed cost as several factors affect the overall cost of this treatment procedure.

Are there any side effects of IVF?

The overall IVF treatment doesn’t have any side effect on the patients. However, the female may experience effects like cramping, bloating, or spotting during the egg retrieval or embryo transfer process.

What is the right time to consult a doctor for infertility?

The doctors usually advise couples to consult after trying to get pregnant for 6 months to 1 year. Women, above the age of 35, who have reproductive health issues should also see an infertility specialist at Pristyn Care.

What are the chances of multiple pregnancies with IVF?

The chances of multiple pregnancies with IVF are slightly higher as multiple eggs are implanted in the embryo to increase the chances of successful pregnancy.

Will there be any restrictions during IVF treatment?

Things that can be bad for the female or male reproductive health are restricted throughout the IVF treatment. Both male and female must avoid smoking, alcohol, caffeine, and stress. Pristyn Care doctors will further guide you in detail regarding the do’s and don’ts during the IVF cycle.

Lifestyle tips to follow for IVF success

For a woman undergoing IVF, every small and big lifestyle habit can play a significant role. From the diet she consumes to the way she lives her life, everything makes a difference.

  • Have good fats – According to a study conducted by the Harvard School of Public Health, consuming a diet rich in monounsaturated fats helps women trying to get pregnant through IVF achieve successful results. These foods not only improve fertility but also help in the growth and development of the fetus. Some foods rich in monounsaturated fats are – nuts, avocados, olive oil, sunflower oil, etc.
  • Say no to alcohol, smoking, and caffeine – Alcohol can affect the normal functioning of the fetus. Women who are trying to conceive should avoid alcohol at all costs. Smoking may severely affect the health of the eggs and sperm. Smoking can cut down your chances of conception through IVF. Consuming more than 200 mg of caffeine per day can also affect the health of the baby.
  • Maintain a healthy weight – Overnight or underweight – neither is good for a healthy pregnancy nor the health of the baby. If you are on either end of the weight spectrum, make necessary changes and achieve a healthy weight. Eat a healthy diet, and include cardio as your basic lifestyle habit. Doing so will increase your chances of a successful IVF.
  • Get enough sleep – Sleep is one the most important factors that decide the success or failure of IVF treatment. 7-8 hours of sound sleep every day is necessary for best outcomes through IVF. Keep electronic gadgets away from your body during sleep hours. Getting sound sleep in a dark environment is believed to regulate the melatonin in the body, which can improve the mental and emotional well-being of the mother.

What happens after an embryo transfer in IVF? – A brief guide

Embryo transfer is the last phase of IVF where the fertilized embryo is transferred and implanted into the uterus of the female. After embryo transfer, your IVF doctor will ask you to stay at the clinic for some time before allowing you to go home. You should ideally wait for two weeks before going for a pregnancy test.

Human Chorionic Gonadotropin (HCG) hormones usually take two weeks to form. After a week of conception, the hCG levels are high enough to be detected in your bloodstream to conclude your pregnancy results. Especially after two week period, HCG levels begin to double every three days. The levels of HCG quickly escalate after 8-11 weeks of your conception.

Once the pregnancy is confirmed, the doctor will guide on the lifestyle and dietary tips that need to be followed for the next 9 months journey.

Read More

In Vitro Fertilization (IVF) | Explained Step by step