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CA 125 Blood Test To Detect Ovarian Cancer
Pristyn Care Team
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The test is used as a tumor marker test, a test that can be used to monitor the treatment of ovarian cancer and detect the recurrence of cancer after treatment. It is important to note that the CA-125 test is not a diagnostic test, but it is an aid in the diagnosis, and it is not recommended as a screening test for ovarian cancer in the general population.
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CA 125 (Cancer Antigen 125) is a protein that is found on the surface of different cancer cells, including ovarian cancer cells. A CA 125 blood test measures the amount of CA 125 in the blood. An elevated level of CA 125 can indicate the presence of ovarian cancer, as well as other conditions such as endometriosis, pelvic inflammatory disease, or even pregnancy. The test is used as a tumor marker test, a test that can be used to monitor the treatment of ovarian cancer and detect the recurrence of cancer after treatment. It is important to note that the CA-125 test is not a diagnostic test, but it is an aid in the diagnosis, and it is not recommended as a screening test for ovarian cancer in the general population.
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How does a CA 125 Blood Test Detect Ovarian Cancer?
A CA 125 blood test measures the amount of the protein CA 125 in the blood. Elevated levels of CA 125 can indicate the presence of ovarian cancer. However, it’s important to note that CA 125 can also be elevated in other conditions, such as endometriosis or pregnancy, so a positive test result does not necessarily mean a woman has ovarian cancer. Additional diagnostic tests, such as an ultrasound or biopsy, are typically needed to confirm a diagnosis.
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What Happens During a CA 125 Blood Test?
A CA 125 blood test is a simple and routine blood test that is typically done in a hospital or clinic setting. The test is usually performed on a blood sample taken from a vein in the arm. The process typically involves the following steps:
- You will be asked to sit down and relax in a comfortable chair or bed.
- A healthcare provider will clean the area on your arm where the blood will be drawn from and wrap a tight elastic band around your upper arm to help the vein fill with blood.
- A small needle will be inserted into the vein, and a small amount of blood will be drawn into a vial or tube.
- The needle will be removed, and a bandage will be placed over the site where the needle was inserted.
- The blood sample will then be sent to a lab for analysis.
- The results of the test will usually be available within a day or two and will be reviewed by your doctor, who will interpret them and explain the results to you.
- It’s a painless test and usually takes only a few minutes.
How Does a Doctor Predict Ovarian Cancer From CA 125 Blood Test?
A doctor will use a combination of factors to predict ovarian cancer from a CA 125 blood test, including the level of CA 125 in the blood, the patient’s age and overall health, and the results of other diagnostic tests.
- Elevated CA 125 Levels: High levels of CA 125 in the blood may indicate the presence of ovarian cancer. However, it’s important to note that CA 125 can also be elevated in other conditions, such as endometriosis or pregnancy, so a positive test result does not necessarily mean a person has ovarian cancer.
- Patient’s age and overall health: Ovarian cancer is more common in older women and women who have a family history of ovarian cancer. So, the patient’s age and overall health also play an important role in the diagnosis.
- Additional diagnostic tests: In order to confirm a diagnosis of ovarian cancer, a doctor may recommend additional diagnostic tests, such as an ultrasound, CT scan, or biopsy. These tests can provide more detailed information about the size and location of any tumors, and can also help to rule out other possible causes of high CA 125 levels.
It’s important to note that the CA 125 test alone is not sufficient for ovarian cancer diagnosis. A positive CA 125 test result prompts further investigation and examination of the patient, including transvaginal ultrasound (TVUS) or pelvic examination.
Also Read: Ovarian Cyst Treatment Cost in India
What are the Limitations of CA125 Blood Test for the Detection of Ovarian Cancer?
The CA125 blood test is a test that measures the amount of the protein CA125 in the blood. Elevated levels of CA125 can be an indicator of ovarian cancer, but it is not a definitive test. The CA125 test has some limitations in detecting ovarian cancer:
- Not all women with ovarian cancer will have elevated CA125 levels. Some women with early-stage ovarian cancer may have normal CA125 levels, while others with advanced-stage ovarian cancer may have only slightly elevated levels.
- CA125 levels can also be normal in some women with ovarian cancer, which can lead to false-negative results.
- The test is not specific for ovarian cancer and may be elevated in other types of cancer, such as lung, breast, or colon cancer.
- The CA125 test is often used along with other tests, such as pelvic examination, ultrasound, and CT scan, to help confirm or exclude a diagnosis of ovarian cancer.
In conclusion, a CA125 blood test is not a definitive test for the detection of ovarian cancer, and its performance is affected by various factors. Therefore, it should be used in combination with other diagnostic methods for more accurate results.
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