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Dolo 650 Uses

Dolo-650 tablet is a common paracetamol medicine often prescribed alone or with one or two medicines to relieve symptoms of:


Nerve Pain

Pain During Periods


Muscle Pain


Common Cold

Sore Throat

Strain Or Sprain


Body Ache

Inflammation Due To Arthritis

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How it Works?

Dolo 650 tablet is a central analgesic like aspirin that reduces pain in the body and anti-pyretic that reduces fever. The tablet blocks the release of the chemical messengers that cause pain and fever . Due to antipyretics the hypothalamus overrides a prostaglandin-induced increase in temperature that helps in lowering the body temperature. After taking Dolo 650 or paracetamol, it takes half an hour to one hour for absorption. The peak effect of paracetamol Dolo 650 starts within one hour after ingestion.

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Dolo 650 tablet with water

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 Dolo 650 capsule with water

Direction for Use

Take the Dolo 650 tablet as a whole with a glass of water or as and when directed by your doctor.

Do not consume more than that which is recommended by your doctor.

Do not chew, crush it or break it.

Do not consume it more than prescribed limit to manage pain.

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Dolo 650 Side Effects

Dolo 650 is a safe medicine without any major side effects. However, in some cases, the following side effects are experienced after a person takes Dolo 650 tablet.

Stomach Pain, Indigestion

Dizziness, Drowsiness

Nausea, Vomiting

Low Blood Pressure


Malaise (Sense Of Not Feeling Well, Fatigue Or Lack Of Interest In Activities)

Safety Advice for Dolo 650

Safety Advice Alcohol


Do not consume alcohol if you are taking Dolo 650 tablet as it may lead to unpleasant side-effects.

Safety Advice Pregnancy


Dolo-650 Tablet is to be taken with caution, specially if you are pregnant.

Safety Advice Kidney


Dolo-650 should be taken with caution, especially if you have a history of Kidney diseases/conditions.

 Safety Advice Driving


Dolo-650 Tablet may affect driving as it causes dizziness.

Safety Advice Breast feeding

Breast feeding

The risks may at times contradict with the benefits and hence it is important to consult with the doctor before taking Dolo 650.

Drug interactions

  • Drug-Drug Interactions: Dolo-650 may interact with blood thinners (warfarin), cholesterol-lowering drugs (cholestyramine), analgesics (aspirin), antibiotics (chloramphenicol, rifampicin), anti-gout medicines (probenecid), antitubercular drug (isoniazid), anticonvulsants (lamotrigine, carbamazepine, phenytoin), and anti-nausea agents (metoclopramide, domperidone).
  • Drug-Food Interactions : Dolo-650 Tablet may interact with St. John's wort (herbal medicine to treat depression). Avoid foods rich in carbohydrates, and pectin including jellies, cabbage, Brussels sprouts and broccoli as Dolo-650 Tablet may interact with these foods. Also, avoid intake of alcohol with Dolo-650 Tablet as it may increase the risk of liver damage.
  • Drug-Disease Interactions: If you have kidney or liver disease, hepatitis, Gilbert's syndrome (a liver condition), hemolytic anaemia (abnormal breakdown of red blood cells), G-6-PD deficiency (a hereditary condition resulting in low red blood cell counts), blood poisoning, inform your doctor before taking Dolo-650 Tablet.

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