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What is IUI?

IUI is the common terminology for Intrauterine Insemination or artificial insemination. It is a fertility treatment where actively motile sperm is implanted into the female’s womb. IUI treatment is mainly done in couples whose sperm cannot reach the fallopian tubes for some health condition. IUI treatment is carried out during ovulation since it increases the chances of successful fertilization. 

IUI has an impressive success rate of almost 80% within 3 to 6 cycles in suitable patients. (Source: Cloudnine Fertility)

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Best Clinics For IUI

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    G-32, Tulsi marg G Block, Pocket G Sector 27 Noida...

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    Pristyncare Clinic image : B-24, Lower Ground Floor Hansraj Gupta Rd Greater Kailash 1...

    Pristyn Care Greater Kailash 1

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Pristyn Care - India's most trusted IUI treatment center with high success rate

Pristyn Care - India's most trusted IUI treatment center with high success rate

At Pristyn Care, we do our best to fulfill your dreams of parenthood. Our team of highly trusted and recognized infertility specialists maps every fertility case and guides every couple before the treatment, so they achieve the best outcome from the IUI treatment. Pristyn Care is trusted as one of the best IUI treatment centers in India that houses some of the best fertility specialists in India. Our fertility doctors have years of experience performing successful IUI treatment for couples with sexual disorders. 

We, at Pristyn Care relentlessly work to provide a wide range of assisted conception options to intending couples. The top fertility specialists provide tailored and dedicated fertility treatment plans specifically designed for you. Additionally, we ensure cost-effective treatment with complete transparency in pricing and NO-cost EMI.

Pristyn Care is committed to delivering a wonderful experience to all the patients who approach us with hope. Our treatments help you embark on the beautiful journey of parenthood.

What happens in IUI treatment?

What happens in IUI treatment?

Before beginning the IUI treatment, the IUI expert shall recommend a few diagnostic tests to determine the exact problem preventing the couple from conceiving a baby. In a common scenario, the following tests are recommended before IUI treatment for the male and the female partner:

Tests for male before IUI treatment

  • Semen analysis – There could be several problems associated with the sperm of a male. To determine the exact, the IUI specialist will need to collect the sperm sample and send it to the lab in a clean container. The semen sample is then analyzed in the lab to determine the problem precisely.
  • Imaging tests – In several conditions, the male is suggested to undergo imaging tests such as MRI or ultrasounds of his genitals to find out if there are any underlying abnormalities with his organs.
  • Testicular biopsy – Testicular biopsy is yet another test to identify and determine abnormalities in the male reproductive system that might contribute to infertility. If the test shows any significant abnormality, the couple might need to use donor sperm to get the treatment done.
  • Hormone testing – Hormone testing estimates the level of testosterone and other male hormones in the male.
  • Genetic testing – Genetic testing helps determine if there is any genetic defect in the genitals of the male that is contributing to problems in conceiving for the couple.

Tests for a female before IUI treatment

  • Ovulation testing – This is done through a blood test that can help determine whether you are ovulating or not.
  • Imaging tests – Often, problems associated with the ovaries and the uterus can contribute to problems for which a couple fails to conceive. Therefore, imaging tests like pelvic ultrasound are mainly recommended to identify if there is any abnormality in the uterus or the ovaries of the women.
  • Test for ovarian reserve – This test can help the doctor determine the number of eggs available in your ovaries for ovulation. To evaluate your ovarian reserve, the IVF specialist may require you to test your hormones at the beginning of your menstrual cycle. If the doctor sees any abnormality associated with your ovarian reserve, the doctor will use an alternative line of treatment.

IUI Treatment explained step-by-step

IUI Treatment explained step-by-step

Step 1: Counseling before IUI treatment – We understand that just like any other fertility treatment, IUI also is a cumbersome process that can be physically and emotionally draining. Hence, at Pristyn Care, we begin the treatment with thorough counseling, after which the doctor plans the treatment process.

Step 2: Ovarian stimulation – Ovarian stimulation begins on the second day of the female partner’s menstrual cycle. The infertility specialist would give oral medicines to stimulate ovulation and then thoroughly monitor the egg production in the ovaries. The ovulation stimulation can also be done by injecting drugs into the female’s body. Oral medications are recommended for 8-12 days and may vary depending on how the ovaries respond. On the other hand, injections are given in parts of the body with a comparatively more significant amount of fat, such as the stomach. 

Step 3: Ovulation monitoring – After the ovarian stimulation, the IUI specialist monitors the development of the follicles. The doctor will likely do hormone tests and ultrasounds to assess the development of the ovarian follicles. Tracking the ovulation helps the doctor decide the best dates when you can begin your IUI treatment for the best possible results.

Step 4: Ovulation trigger – When the ovarian follicle shave develops and reaches the desired shape and size, hCG injection is given to the female to trigger ovulation. Ovulation generally happens 36 hours after the trigger shot.

Step 5: Sperm harvesting – For IUI treatment, the couple and the doctor may decide whether to use fresh sperm or frozen sperm. If the couple decides to use fresh sperm, the male partner or the donor must produce it at the fertility clinic by masturbating. If the couple decides to use frozen, they can contact any of the infertility treatment labs nearby. Frozen sperm is defrosted and then washed to remove the impurities before they are used for the treatment.

Step 6: Insertion of sperm – Once the female ovulates and the sperm is washed out of all impurities and dirt; the doctor uses a thin, flexible catheter to implant the sperm into the female partner’s uterus. Unlike IVF, IUI does not involve any painful steps. However, the insertion of the catheter may cause the female to feel slight cramps and discomfort.

Step 7: Pregnancy test – This is the last step of the IUI treatment, wherein the doctor checks whether or not the treatment has been successful. This test can be done two weeks after the sperm has been implanted in the uterus. If the pregnancy is not successful, the doctor might repeat the entire procedure or may suggest another line of treatment.

How to prepare for IUI treatment?

How to prepare for IUI treatment?

Here are a few steps to help you better prepare for the procedure. Some of the best practices to maximize the outcome of IVF treatment are:

  • Maintain a healthy weight
  • Eat a healthy, well-balanced diet
  • Start taking prenatal supplements
  • If you are planning for IVF, quit smoking, drinking alcohol and other recreational drugs
  • Practice yoga, meditation, and journaling to maximize the outcomes of your IVF treatment.
  • Live a stress-free life. Trust the treatment process and remain hopeful. 

When should you consult a fertility expert for IUI treatment?

When should you consult a fertility expert for IUI treatment?

You should consult an IUI specialist when you and your partner have unprotected sex for more than a year but fail to conceive. You may try on your own for as long as you want, but getting medical help without delay is the best decision. 

Pristyn Care fertility experts suggest consulting a fertility expert when a couple fails to conceive even after indulging in unprotected sex for a year. Additionally, a couple may consult a fertility specialist for IUI treatment in case of the following:

  • The female partner has ovulation disorders, does not ovulate regularly, or has PCOD/ PCOS
  • Couples with unexplained infertility
  • If the male partner has semen abnormalities or ejaculation disorder
  • Anyone who needs donor sperm, such as LGBT couples, heterosexual couples struggling with male factor infertility, or single women looking to conceive.

What are the advantages and disadvantages associated with IUI treatment?

What are the advantages and disadvantages associated with IUI treatment?

IUI is a viable fertility treatment for couples with unexplained fertility, low sperm count, and male factor infertility. IUI is a relatively simple procedure and consists of three main steps:

  • Ovulation tracking to identify the best fertile period
  • Collection of sperm
  • Iplantating the sperm into the uterus

Here are some of the advantages and disadvantages of IUI treatment:

Advantages of IUI:

  • IUI is less expensive than IVF or ICSI.
  • IUI exerts less stress on the body.
  • The sperm-washing process enhances the chances of sperm quality.
  • IUI is not a painful procedure and hence does not require anesthesia.
  • IUI treatment does not take more than 15-20 minutes. So, the female does not require any hospitalization and can return home just after resting for 20 minutes after the procedure.

Disadvantages of IUI

Although IUI is a viable fertility treatment option, it has some challenges too. Some of the common disadvantages of IUI are:

  • IUI cannot be carried on if the female does not ovulate.
  • The sperm used should be of high quality, i.e., it should have good motility.
  • The success rate of IUI is only 20-25 percent compared to IVF treatment.
  • The risk of multiple pregnancies is relatively high IUI due to the intake of fertility drugs.

Case Study

Case Study

“IUI was a boon for us when nothing else worked.”

Sravanti (name changed, 32 years old) and Prateek (name changed, 34 years old) were struggling to conceive. They had been married for 6 years now. They had consulted several fertility specialists in Kolkata (their hometown) but were disappointed when nothing worked in their favor. They almost gave up hope, decided to adopt a child, and had already begun the process. But, as luck would have it, in December 2020, Prateek shifted to Delhi for his job and on a friend’s recommendation, got in touch with Pristyn Care.

“It is harder than one can imagine. The disappointment drained both of us. We held onto hope for a long time and almost gave up. But, I thank my destiny that it brought us to a new city that changed our lives forever,” Prateek shared.

Ritika was consulted by one of the best and highly trusted fertility specialists in Delhi who works with Pristyn Care. She was diagnosed with a minor blockage in the fallopian tubes, but the upside was that she was ovulating. Considering all the factors, the doctor recommended IUI since they have already exhausted enough money consulting doctors in the past 2 years. Everything fell in place, and Ritika conceived a baby boy in her second IUI cycle.

“We can’t be more thankful to Pristyn Care. It still feels like a dream, but when I look at the little boy, I know we are living the joys and blessings of parenthood,” says Ritika.


When is the best time for an IUI treatment?

There is no specific answer to this. IUI doctors have different approaches to seeing this. Ideally, medical practitioners believe that IUI should be performed within 6 hours of ovulation. However, conducting the IUI process at 24 hours is also very common. If two inseminations are planned, the IUI is usually planned 24 and 48 hours after the surge is detected.

Is IUI treatment painful?

For most women, IUI is a relatively painless fertility treatment. However, some women may find the speculum insertion uncomfortable if it is not lubricated. Also, in very few cases, the catheter might cause problems if the woman’s cervix is very narrow.

What does an IUI feel like?

According to most women, the feeling of undergoing IUI is similar to having a pap smear; there is a little discomfort, but the treatment is relatively painless. They feel the same when the catheter is inserted into the cervix. Some women experience bloating, and cramps due to the medications used or injected during the ovulation stimulation process.

What to expect during IUI treatment?

You may experience some cramping and spotting after the IUI procedure. There should be no pain, but only slight discomfort. You may also expect unusual vaginal discharge, which is normal. If you develop any infection in the vaginal site, consult with your fertility specialist without delay.

What fertility drugs are used to stimulate ovulation in IUI?

The most common oral drug used to induce ovulation is Clomiphene Citrate. Usually, the doctor prescribes 50 mg of the medicine for 5 days to induce ovulation. If there is no ovulation, the doctor may increase the dosage. The other common drug is Aromatase Inhibitors. These drugs need to be taken early in the menstrual cycle. Finally, fertility hormones like a follicular stimulating hormone (FSH) and human menopausal gonadotropins (HMG) are the common drugs used to induce ovulation.

How long does it take to get pregnant with IUI fertility treatment?

Since insemination occurs during ovulation, it takes approximately two weeks after the procedure to determine if the treatment is successful after a positive pregnancy test.

How soon after IUI can I take a pregnancy test?

You will be asked to come to the clinic for your pregnancy test (done via blood draw) 9 to 14 days after your IUI procedure.

Can the sperm fall out after implantation?

No, once the sperm is implanted into the uterus, it does not fall out. However, if there is too much wetness after the catheter is inserted and loosens the cervix, the sperm might flow out. To make sure that the whole procedure is conducted with precision, it is essential to undergo treatment from experienced IUI specialists in India.

What is the success rate of IUI?

Depending upon the cause of infertility, the success rate of IUI treatment can be anywhere between 14 to 21 percent per cycle. The rate of multiple gestation pregnancies is 23-30% when fertility drugs are used. The success rate of IUI highly depends upon the age of the female and the quality of the sperm used.

Which fertility treatment is better - IUI or IVF?

Both IUI and IVF are very commonly performed fertility treatments adopted by people all over the world. But which one is the right treatment for can be answered only after a thorough evaluation by the fertility specialist. Ideally, couples dealing with infertility start with the IUI process, which is less invasive and less expensive. But the success rate of IVF treatment is much higher than IUI. Every patient and situation is different, so you should meet with a fertility specialist to review your history and discuss the course of action.

How many IUIs should I try before moving on to IVF?

If you are under 35 years of age, most doctors will suggest 3 to 6 cycles of IUI before moving to IVF treatment. However, for women above 35 years of age, the chances of you conceiving through IUI may be less. So, if you are above 35 years of age, you must consult a fertility specialist to check which option is best for you.

Can IUI be done at home?

IUI is almost always performed by a medical professional at a fertility clinic or hospital. However, that doesn’t mean IUI can’t be done at home. In many parts of India, trained midwives perform IUI treatment at home.

What are the common side effects of IUI treatment?

Common side effects of IUI treatment include mood swings, hot flashes, depression, nausea and vomiting, visual disturbances, abdominal bloating, breast tenderness, swelling and rashes around the injection site, and ovarian hyperstimulation syndrome.

For how long does washed sperm live?

Washed sperm normally live for 6-12 hours, but sometimes as long as 24 to 48 hours. But, it should not be kept for too long. For the best outcome, it is advisable to perform the insemination within 3 hours.

When can we have sex after IUI?

Usually, one can have intercourse anytime after an IUI. But if there was any bleeding or complication during the IUI, some doctors may suggest waiting for 2 days before having intercourse.

What is the IUI Treatment Cost in India?

The minimum cost of IUI (Intra Uterine Insemination) can be as low as 10,000 INR and can go at a maximum of 15,000 INR.

What is the IUI treatment cost in India?

What is the IUI treatment cost in India?

IUI is considered a relatively affordable fertility treatment, and its one cycle is priced between Rs. 10,000 to 15,000. You should note that this is the estimated cost of only one cycle of IUI. In several cases, patients require multiple cycles to see effective results. Some other factors that affect IUI treatment costs in India, include:

  • Consultation fees of the fertility specialist
  • Cost of donor sperm
  • Cost of medicines for ovulation stimulation
  • Charges of follicular monitoring
  • Number of IUI cycles
  • Choice of treatment city
  • Preference of treatment hospital or fertility clinic
  • Age of the couple
  • Cost of lab tests
  • Post-treatment consultation charges

Consult with best Fertility specialist at Pristyn Care and Get the cost estimate of IUI treatment.


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