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What is IVF?

In Vitro Fertilization (IVF) is India’s most common assisted reproductive technique. About 2-2.5 lac IVF cycles are done annually in India alone. IVF involves fertilizing the eggs with sperm in a vitro dish at a laboratory in a carefully observed environment. Vitro is a Latin word that translates to ‘glass’. Hence, the process means fertilization that takes place in a glass.

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      Pristyn Care - India's most trusted IVF treatment center with high success rate of IVF

      Pristyn Care - India's most trusted IVF treatment center with high success rate of IVF

      Pristyn Care is widely trusted and recommended as the most trusted IVF treatment center in India for test-tube babies. The customized fertility treatments at Pristyn Care have helped hundreds of couples struggling with fertility issues. At Pristyn Care, we offer the best and most world-class IVF treatment at an affordable price. Each of our fertility treatment centers is equipped with world-class infrastructure to help a couple conceive naturally while achieving the most favorable outcomes. Additionally, we maintain an extreme level of transparency at every step of our treatment journey.

      Pristyn Care takes pride in having some of the best IVF specialists in India. Each of our fertility doctors comes with extensive years of experience in performing successful IVF treatment for cases of male infertility, female infertility, unexplained infertility, low ovarian reserve, etc.

      Pristyn Care IVF treatment team is committed to delivering a wonderful experience to all the patients who approach us with hope. Our treatments are tailored to help you embark on the beautiful journey of parenthood. We have a brilliant team of doctors and our medical support team is also trained to provide the necessary emotional support to ensure every couple receives a stress-free and hassle-free experience.

      What happens in IVF?

      What happens in IVF?

      Before proceeding with IVF treatment, it is essential to determine where exactly the problem lies. The male and female partners need to undergo specific tests so that the infertility specialist can evaluate and determine the best treatment.

      Test for men for IVF

      In males, the IVF doctor would conduct a general physical exam of his overall health and then examine the genitals. Specific tests in the case of men before IVF may include:

      • Semen analysis – The semen is generally collected in the lab in a clean container by masturbating. The semen specimen is sent to the lab for analysis.
      • Hormone testing – A man might also be asked for a blood test through which the doctor may evaluate the level of testosterone and other male hormones in his body.
      • Imaging tests – In some instances, the male is suggested to undergo imaging tests such as an ultrasound or MRI of his genitals to confirm if there is a presence of any abnormalities.
      • Vasography – This imaging test is done to check for any damage or blockage in the vas deferens, which is a long tube in males that connects the pelvic cavity to the epididymis. The vas deferens are responsible for transporting mature sperm to the urethra.
      • Testicular biopsy – A testicular biopsy is recommended to identify any abnormalities in the male reproductive system that might contribute to infertility.
      • Genetic testing – This test determines whether a genetic defect might contribute to infertility-related problems in a male.

      Tests for women

      Like men, women need to undergo specific tests too, which can help the IVF specialist determine how IVF or other assisted reproductive technology might work best for the couple. The tests that are commonly recommended for women before IVF are:

      • Ovulation testing – This is done through a blood test that can help determine whether you are ovulating or not.
      • Test for ovarian reserve – This test can help the doctor determine the number of eggs available in your ovaries for ovulation. To evaluate your ovarian reserve, the IVF specialist may require testing your hormones at the beginning of your menstrual cycle.
      • Imaging tests – Often, problems associated with the ovaries and the uterus can contribute to problems for which a couple fails to conceive. Therefore, imaging tests like pelvic ultrasound are mostly recommended to identify if there is any abnormality in the uterus or the ovaries of the women.
      • Hysteroscopy – In some instances, the gyne specialist or the infertility specialist may also require you to undergo a hysteroscopy. In hysteroscopy, the doctor would insert a flexible, thin, lighted medical instrument through the woman’s cervix to view inside her uterus and check if any abnormality is present.

      What happens during IVF? Step-by-step of IVF

      What happens during IVF? Step-by-step of IVF

      Step 1: Beginning of your treatment

      The IVF treatment journey begins with the doctor determining the best time during your menstrual cycle. IVF treatment requires several eggs to mature.

      Step 2: Ovarian stimulation

      This step is where the doctor stimulates the ovaries to promote the growth of the follicles that contain the eggs. The common hormones in the medications used to stimulate the follicles are Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). Once injected, the IVF doctor and the team monitor how the ovaries respond to the medications.

      Step 3: Trigger Injections

      Once the doctor sees that the egg follicles in the ovaries are enough, the ovarian stimulation would be ended. During this phase, the doctor would stop the LH and FSH injections and would recommend the time when you need to administer trigger injections. The trigger injection includes injecting human chorionic gonadotropin (hCG) to mature the eggs and help them get released from the ovarian follicle wall.

      Step 4: Egg retrieval

      This step is also known as the ‘egg picking stage.’ This daycare procedure is done under general anesthesia and is considered the only painful phase in IVF. During the procedure, the doctor inserts a fine needle with an ultrasound-guided probe through the vaginal canal of the woman to retrieve her mature eggs. The procedure generally does not take more than 30 minutes. On average, 8-15 eggs are collected during this process. Once the eggs are retrieved, the patient is allowed to go home and rest. It is best if the patient is accompanied by her partner or someone else who can help her drive and reach home safely.

      Step 5: Sperm collection

      After retrieving the eggs, the IVF doctor will need to collect the sperm from the male partner. The male partner will be asked to produce his semen specimen. Every IVF lab will have a dedicated room where the male can masturbate and give his sperm/ semen specimen. The male partner can produce his semen specimen at home or at the clinic where the semen specimen would be stored. If the couple wants to use donor sperm or frozen sperm, the IVF team will prepare it in the lab.

      Once the sperm is collected, it will be washed with medicine under a microscope to eliminate all sorts of dirt and debris. This is an essential step of IVF as it gives the perfect sperm, which will have a fair chance to fertilize the eggs retrieved from the female. A perfect healthy sperm is not very long and not too short either, not too fat or not too thin.

      Step 6: Fertilization

      Once the sperm is washed and concentrated, it is placed in an incubator along with the eggs for fertilization. The process is very similar to natural fertilization, where ‘sperm meets eggs’ inside a human body.

      Step 7: Embryo development

      The eggs that the egg would fertilize would then turn into an embryo. The IVF specialist will collect the embryo, place it in a unique incubator and monitor its growth for the next 4-6 days. The developed embryo would be mixed with amino acids to its growth. If the embryo’s growth is consistent, it will likely turn into a 4-8 cell embryo by the 4th day.

      Step 8: Embryo transfer

      In the most straightforward description, embryo transfer refers to the process of transferring the developed embryo from the incubator and implanted in the uterine wall. This process is quick, does not take more than 20 minutes, and can be done at the doctor’s clinic. The woman would be asked to lie down on her back and spread her legs during the process. The doctor will collect the embryo with a very soft, flexible, and thin catheter. Then, using a speculum, the doctor will open the cervix and insert the catheter through the cervix into the uterus.

      An abdominal ultrasound is conducted to ensure that the tip of the catheter places the embryo at the best location for embryo implantation. After the embryo implantation, the woman will be asked to remain in the lithotomy for some time so that the embryo doesn’t come or fall out. Then, she can head home once the process is over.

      Step 9: Pregnancy check

      The woman would be called to the clinic after 2 weeks for a blood test that checks the presence of hCG in the blood. If the blood test shows the presence of hCG in it, the pregnancy is successful. If the results are positive, the doctor would suggest the best pregnancy care tips to the woman and encourage her to limit strenuous physical activities.

      How to prepare for IVF?

      How to prepare for IVF?

      IVF can be a physically and emotionally challenging procedure. But some steps can help you prepare for the procedure better. Some of the best practices to maximize the outcome of IVF treatment are:

      • Maintain a healthy weight
      • Eat a healthy, well-balanced diet
      • Start taking prenatal supplements
      • If you are planning for IVF, quit smoking, drinking alcohol and other recreational drugs
      • Practice yoga, meditation, and journaling to maximize the outcomes of your IVF treatment.
      • Live a stress-free life. Trust the treatment process and remain hopeful.

      When is IVF treatment recommended?

      When is IVF treatment recommended?

      IVF can be a viable treatment for:

      • Women who are suffering from endometriosis. 
      • Women who have partially or fully blocked fallopian tubes. 
      • Women who have passed her reproductive age where conceiving naturally gets tough.
      • Couples who are dealing with unexplained infertility.
      • Couples who deal with male factor infertility, low sperm motility or low sperm count.

      Risks and complications involved during IVF treatment

      Risks and complications involved during IVF treatment

      IVF is a safe reproductive technique, and when performed under the guidance of an expert fertility specialist, there are very few chances of complications involved in the procedure. However, throughout the procedure, there might be some complications involved at different stages of the treatment, such as:

      • Bruising – Mild bruising and soreness at the injection sites during ovarian stimulation is a common complication associated with IVF.
      • Reaction to medications – At the beginning of IVF, the patient is given a high dose of medications for several weeks. This may cause nausea and vomiting in several women.
      • Allergies – Many women complain of allergic reactions, itching, and redness at and around the injection site.
      • Reaction to hormonal imbalance – Due to the medications, the woman might suffer from breast tenderness, vaginal discharge, and unusual mood swings.
      • Ovarian hyperstimulation syndrome (OHS) – OHS is an abnormal reaction to excess hormones. The condition occurs as a reaction to hormonal medications that stimulate the development of eggs in the ovaries. In this condition, the ovaries become painful and tend to become swollen. In rare situations, OHS can lead to kidney failure and blood clots in the ovaries.
      • Multiple births – In the case of IVF, there is a risk of multiple embryos getting transferred to the uterus. The transfer of multiple fetuses increases the risk of early labor.
      • Miscarriages – The rate of miscarriage in case of IVF is significantly higher than in normal pregnancies.

      Case study

      Case study

      “We are feeling so blessed. There is no joy like parenthood.”

      Ritika (name changed, 34 years old) and her husband Amrit (name changed, 38 years old) had been trying to conceive for the last 6-7 years. They consulted many doctors but could not find anyone with the kind of commitment required for the treatment process. The doctors they checked with told them that both the partners were completely healthy and they did not require any medical intervention. They trusted their words and kept trying for a baby, only to be disappointed month after month and year after year. 

      Ritika used to track her ovulation and plan intercourse as the doctors guided her. Eventually, they lost hope and gave up on the plan of being parents. It seemed too much of an effort for both of them. 

      “When nothing worked, we consulted a few fertility specialists in Delhi NCR who quoted us hefty amounts. We knew fertility treatments are expensive but what they had asked was way beyond our budget. We did not have that much money for a treatment,” said Ritika.

      After 11 years of marriage, Ritika and Amrit decided to give one last shot for the treatment. And they approached Pristyn Care for IVF treatment. With the guidance of one of the best fertility specialists in Delhi NCR, Ritika and Amrit underwent IVF treatment and are proud, happy parents to two lovely twin daughters.

      “Affordability was a big relief for us at Pristyn Care. The doctor did not give us any false hope; she only guided us with the best of her professional experience. She made us believe and hope. And things did turn into a reality so wonderfully like we never expected. Our married life has found a new meaning. We are so happy and thankful,” says the couple.

      FAQ

      Is IVF treatment painful?

      IVF treatment is not a painful procedure. The only stage that might cause discomfort is the egg retrieval stage. Other than this, most patients do not feel any pain except for little cramps and bloating.

      What are the side effects of IVF treatment?

      IVF treatment doesn’t have any side effects on the patient. However, the female may experience cramping, bloating, or spotting during egg retrieval or embryo transfer.

      What is the right time to consult a doctor for IVF?

      Women over the age of 35 years should approach an infertility specialist for IVF treatment after trying to conceive for one year. As a woman approaches her mid-30s, her chances of getting pregnant decrease. At that age, a woman should consult a fertility specialist to check her ovarian reserve and take necessary guidance.

      How many cycles will it take for successful conception?

      Some patients can conceive in the first IVF cycle successfully. However, if the first attempt is unsuccessful, the patients usually have to go through 3-4 cycles to conceive without complications.

      How much time does an IVF cycle take?

      Usually, one complete cycle of IVF takes around 1-3 weeks. However, the doctor may split these steps into different parts, which can take longer.

      How long does it take to get pregnant after IVF treatment?

      One cycle of IVF treatment takes around two months. However, research suggests that women younger than 35 will get pregnant and have a baby with their first IVF egg retrieval and subsequent embryo transfer(s) about half the time.

      What happens if a woman doesn't get pregnant during the first cycle of IVF?

      If a woman doesn’t get pregnant with the first cycle of IVF, she still has a perfect chance of getting pregnant with the second, third, or even more cycles of IVF.

      Can donor eggs be used for IVF?

      Yes, you can use the donor egg or sperm as both are viable and you have undergone the appropriate procedures to prepare your uterus for transfer.

      Do donor eggs or sperm affect the treatment outcome?

      No, donor eggs or sperm don’t affect the treatment outcome.

      Are IVF babies healthy?

      Yes, an IVF baby is usually normal and healthy. Millions of babies across the globe are born using IVF, which is entirely normal. The only difference between IVF babies and normal babies lies in the process of fertilization. After that, the rest of the pregnancy is as regular as a normal pregnancy.

      Can a woman with uterus disease undergo IVF treatment?

      It depends on several factors, such as the disease type, cause, and severity. You can book an appointment and consult online/offline with our highly experienced IVF experts to know more about the same.

      How does age impact the success rate of IVF treatment?

      The success rate of an IVF treatment depends highly on the woman’s age. As a woman ages, her chances of having a successful pregnancy gradually go down. If she is using her eggs:

      • If the woman is below 35 years of age, the percentage of live births per egg retrieval is 54.4%.
      • For a woman between 35 to 37 years of age, the percentage of live births per egg retrieval is 42%.
      • For a woman between 38 to 40 years of age, the rate of live births per egg retrieval is 26.6%.
      • For a woman aging between 41 to 42 years, the rate of live births per egg retrieval is 13.3%.
      • If the woman ages 43 or above, her chances of live births per egg retrieval goes to as low as 3.9%.

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