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Weight Loss Injections​: Types, Uses & Benefits

Curious about weight loss injections? Explore various types, their uses, and how they can help you achieve your weight loss goals effectively.

Curious about weight loss injections? Explore various types, their uses, and how they ... Read More

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What Are Weight Loss Injections​?

Weight loss injections have recently gained widespread attention as an emerging effective weight loss treatment for those struggling with obesity. They mimic GLP-1(glucagon-like peptide-1) hormone, which the body releases after eating, and are hence called GLP-1 agonists. GLP-1 agonists were initially designed for type 2 diabetes treatment by triggering the release of insulin into the bloodstream. Additionally, GLP-1 slows down the digestion and reduces the appetite, which makes you feel fuller even after eating less. Consequently, you eat less and feel less hungry while also losing weight.

Weight loss injections are administered under the patient’s skin for a long period of time on a regular basis to help with weight loss. People with a BMI of 27kg/m2 or higher and those with other weight-related issues, are may be recommended for weight loss injection.

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Benefits of Weight Loss Injections

Several benefits of weight loss injections have been given below

  • Reduces the person’s appetite, which decreases the calorie intake, consequently
  • Increases the feeling of fullness even after eating a little
  • Lowers blood sugar levels
  • Manages excessive weight and obesity
  • Curb an individual’s preference for high-fat foods
  • Prevent the development of weight-related health conditions, such as type 2 diabetes, high blood pressure, or heart disease
  • delay gastric emptying, which can help with blood sugar management

Mostly Used Weight Loss Injections​

Wegovy (semaglutide)

Wegovy helps in managing weight loss in people struggling with obesity and blood sugar levels in people struggling with type 2 diabetes, while also reducing the risk of cardiovascular issues. Wegovy can be injected into the skin of the arms, stomach, or buttocks once a week. It should be administered on the same day each week, and at the same time, if possible, in order to maintain consistency. The doctor may ask you to consume a low-calorie diet along with a regular exercise routine for maximum results. People with a family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (MEN 2) should always discuss with a doctor before taking the injection. 

 

Mounjaro

Mounjaro helps in reducing the weight for people struggling with obesity(BMI>=30) and people who are overweight(BMI 25-30) by decreasing the appetite and hunger. The mounjro 2.5mg injection is being administered once a week in the abdomen, thigh, or upper arm. In order to prevent skin irritation and ensure proper absorption of the medicine, it is recommended to rotate the injection sites. For the maximum and effective outcomes, it is advised to take the Mounjaro injection for weight loss​ on the same day each week. 

Pregnant and lactating women or those trying to conceive should avoid taking the injection or discuss it with a doctor before doing so. Consult a doctor to understand the usage, dosage, timings, and storage of Mounjaro 2.5mg injection. Avoid freezing the medicine, but keep it in a refrigerator under a temperature of 2°C–8°C.

 

Zepbound

Zepbound helps in managing and reducing weight and is also useful in obstructive sleep apnea. The injection is administered once a week under the skin, and your doctor may ask you to adhere to a healthy diet and a regular exercise routine. 

Zepbound has been known for effective chronic weight management in adults who are obese with a BMI of 30 kg/m2 or higher, and overweight with a BMI of 27 kg/m2 or higher. Additionally, it also helps in addressing high blood pressure, high cholesterol, type 2 diabetes, obstructive sleep apnea, or cardiovascular disease. Nausea, diarrhea, indigestion, and constipation are a few of the common side effects of Zepbound. 

 

Ozempic

Ozempic mimics a GLP-1, a hormone released from the digestive tract, and promotes the feeling of fullness. The body makes more GLP-1 when you take Ozempic, which naturally suppresses your appetite. Ozempic is injected on a weekly basis in your thigh, abdomen, or upper arm. The doctor may recommend eating smaller meals and staying hydrated in order to reduce the gastrointestinal side effects. 

 

Saxenda

Saxenda is a popular injectable medicine used in adults struggling with obesity or who are overweight. It is also helpful to lose weight in children in the age group of 12-17 years and having a body weight above 60 kg. The doctor may advise you to increase physical activity and consume the medication with a reduced-calorie diet. The medicine is not safe to consume for children under 12 years of age and within the age group of 12 to 17 years with type 2 diabetes. 

Weight Loss Injections Side Effects​

The following are the risks and side effects associated with taking weight loss injections. However, these can be minimized by beginning with the low dosages. 

  • Nausea & bloating
  • Diarrhea & constipation

Additionally, people with the following health conditions are at a higher risk of developing more side effects. To avoid overdosage, it is essential to address the root cause of obesity for visible weight loss.

  • Gut issues 
  • Mental health issues
  • Eating disorders such as anorexia nervosa
  • Thyroid cancer, such as multiple endocrine neoplasia type 2(MEN2) syndrome or medullary thyroid cancer

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Ozempic vs Mounjaro

Feature Ozempic  Mounjaro
Generic Semaglutide Tirzepatide
Drug class GLP-1 receptor Dual GIP/GLP-1 receptor
Mechanism Mimics GLP-1 hormone to reduce appetite  Mimics both GIP/GLP-1
Dosage  Up to 2 mg is usually administered Available in 2.5 to 15 mg dosages weekly
Frequency Once a week Once a week

Weight Loss Treatment Options

Medications for Weight Loss

Depending on your lifestyle, medical and weight history, eating habits, and dietary needs, your doctor may prescribe certain weight loss pills that help in controlling the appetite and regulating weight gain 

 

Surgeries for Weight Loss

Bariatric surgery is an effective surgical weight loss procedure for people struggling with class III or morbid obesity. It works through modifying our digestive system. Below are the three commonly employed bariatric procedures. 

  • Gastric sleeve:
    The procedure removes approximately 80% of your stomach, leaving behind a small portion, like a sleeve. Consequently, it makes you feel full sooner and reduces the amount of food you can eat.
  • Gastric bypass(Roux-en-Y):
    Using surgical staples, surgeons first make a small pouch at the top of your stomach and separate it from the lower part. After that, doctors divide your small intestine and bring the newly formed segment up to join the stomach pouch. Now, food will travel via the lower section of your small intestine and the new, smaller stomach, bypassing the rest.  This limits the amount of food your small intestine can absorb and the amount your stomach can hold.
  • Biliopancreatic Diversion with Duodenal Switch (BPD-DS). This procedure bypasses about 75% of your intestine, reducing the hunger hormones produced in your small intestine and stomach

Frequently Asked Questions

What is the diabetic injection for weight loss​?

Weight loss injections such as semaglutide, tirzepatide, etc., help in managing weight loss through reducing appetite and slowing down digestion. These also help in controlling the blood sugar levels.

How much do weight loss injections cost?

The entire cost of administering the weight loss injections is dependent on the type of medication prescribed, insurance coverage, and the entire treatment plan.

Are weight loss injections safe?

Weight loss injections have been proven to be an effective method of addressing obesity. However, these should be taken only under the guidance of a healthcare professional. Common side effects associated with the weight loss injections are nausea, vomiting, diarrhea, etc.

Is Ozempic approved in India?

India’s Central Drugs Standard Control Organisation (CDSCO) has officially approved the use of Ozempic, a once-a-week injectable drug for people struggling with weight gain and type 2 diabetes.